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Showing posts with the label CRISPR

How Macrophages Switch to Attack Mode: New Molecular Timeline Study Unveiled

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  The immune system is a marvel of biological engineering, a complex network of cells and molecules that work tirelessly to protect us from pathogens like bacteria , viruses , and even cancer cells . Among the immune system’s first responders are macrophages —aptly named from the Greek for “big eaters”—which engulf and destroy invaders while coordinating broader immune responses. But how do these cells transition from a state of rest to a full-on attack mode with speed and precision? A groundbreaking study published on August 8, 2025, in *Cell Systems* by researchers at CeMM Research Center for Molecular Medicine and MedUni Vienna offers a detailed molecular timeline of this process, shedding light on the intricate regulatory programs that govern macrophage activation. This article dives into the study’s findings, explores their implications, and considers how this knowledge could shape the future of immunotherapy and precision medicine . #### The Role of Macrophages: The Body’...

GENETICS - COMPLETE GUIDE AND SCIENTIFIC INFORMATION

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  Introduction - Genetics is the branch of biology that studies genes, heredity, and variation in living organisms. At its core lies the understanding of how traits are transmitted from parents to offspring, how genetic information is encoded, expressed, and regulated, and how genetic diversity arises across populations and species. From the discovery of DNA’s double helix to the latest CRISPR genome-editing tools, genetics has revolutionized medicine, agriculture, biotechnology, and our very perception of life. 1. Historical Milestones Pre-Mendelian Observations (Ancient–17th Century): Early breeders of plants and animals noted that offspring often resembled their parents, yet patterns were not formally studied. Gregor Mendel (1822–1884): In 1865, Mendel published his experiments on pea plants, revealing particulate inheritance and formulating the laws of segregation and independent assortment. Mendel’s work went largely un...